There is no specific treatment your veterinarian has that kills Canine Coronavirus. What we try to do is support the pup until its own immune system conquers the virus. We do this by correcting the dehydration that accompanies all severe diarrhea. If the puppy can drink, Pedialite is a good oral liquid to give them. If they are sicker, the fluids need to be given intravenously or subcutaneously.
For The Diarrhea
We give medicines that relax intestinal spasms such as Metoclopramide. In severe cases, we might also prescribe Loperamide, oral Opiods, or Diphenoxylate (Lomotil).
Compounds that protect the inner surfaces of the inflamed intestines can also be helpful. Common ones include: Famotidine (Pepcid), Cimetidine (Tagament), and Sucralfate (Carafate). But we can not use them until the vomiting has been controlled.
Medications that stop vomiting are called anti-emetics. We often inject one called Metoclopramide (Reglan). Chlorpromazine (Thorazine) and Prochlorperazine (Compazine) are also used. Sometimes, Pepto-Bismol in small amounts is helpful.
Antibiotic Protection Antibiotics do not destroy Coronavirus. We often, however, give them to give the pup to protect from other bacteria that may attack its weakened system.
For General Support
Chilled puppies need additional sources of heat such as a heating pad or heat lamp. Many of these puppies have internal parasites that complicate the disease. If Protozoa is detected in fecal samples, puppies are placed on Metronidazole (Flagyl). If hookworms are detected, the pup is wormed with Pyrantel Pamoate. Puppies are typically left to heal their intestines for 2 days, before given food by mouth. Food is then given to them in frequent small amounts of a bland intestinal diet.